DCDB: Drug combination database
نویسندگان
چکیده
منابع مشابه
DCDB: Drug combination database
SUMMARY Rapid advances in pharmaceutical sciences have brought ever-increasing interests in combined therapies for better clinical efficacy and safety, especially in cases of complicated and refractory diseases. Innovative experimental technologies and theoretical frameworks are being actively developed for multicomponent drug research. In this work, we present the Drug Combination Database, wi...
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Experience in clinical practice and research in systems pharmacology suggested the limitations of the current one-drug-one-target paradigm in new drug discovery. Single-target drugs may not always produce desired physiological effects on the entire biological system, even if they have successfully regulated the activities of their designated targets. On the other hand, multicomponent therapy, i...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2009
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btp697